Hello.
No worries.
You change only the Loading IOS for the Game not more.
You can try Slot 248/249/250/251.
That is why you can change the cIOS for any of these Slots with d2x cIOS Installer.
Today with the actual USBLoader GX/WiiFlow/Configurable USBLoader MOD,cIOS 249[57] d2x v8/v10 and/or 250[56] d2x v8/10 works for most of the Games.
If you want to
experiment with them you can install some other Versions to Slot 248 and 251.
For Example:
IOS248[57] (rev 21, Info: d2x-v8final): Trucha Bug, NAND Zugriff, USB 2.0
IOS249[57] (rev 65535, Info: d2x-v8final): Trucha Bug, NAND Zugriff, USB 2.0
IOS250[56] (rev 21008, Info: d2x-v8final): Trucha Bug, NAND Zugriff, USB 2.0
IOS251[56] (rev 21, Info: d2x-v10beta52): Trucha Bug, NAND Zugriff, USB 2.0
With such an Setup you can make near 99 Percent of the Wii Games with maybe any USB Device with one of the 3 USBLoaders working.
But it is
NOT NECESSARY.
Thank you.