On old3ds, yes with rxTools emunand.
Maybe on new3ds with the gateway launcher in classic mode emunand.
Ah, yes, didn't think about that. I'll wait for the DS profile exploit to come out anyways, but if it's not out on Wednesday, I won't be able to boot to CFW again then, going to a friend who has Cubic Ninja, I don't have it myself, so that's why I asked when not on CFW.
Thanks.
And when on CFW, I can use a firmware spoofer to be able to boot games that requires a higher firmware than 4.5?