You are serious right? You came here and actually asked 'is it possible' as if there might be some chance it wasn't?
What you likely need, is a program like IMGburn, or something comparable, that makes absolute copies of discs. It's not radically new.
An easier solution, just let someone do it for you, as it is no real challenge to download image files of ANY game that is essentially marketed on a digital disc be it cd dvd or blueray. Granted, burning blueray is still the realm of the geek as it is a bit higher end skill set (at this time).
Here is your only real barrier. Last time I checked, NO ONE actually took in used PC games, and guess why that is?
You guessed it, because of what you wish to do.
Now to my knowledge some European countries have laws that allow you to return goods within a specific time span including PC games. I am sure that is limited to UNOPENED games, otherwise the PC game industry in Europe would simply not exist. I know myself, if I owned a game store, you could forget buying PC games in my store, if you could legally demand they be returnable even sealed.
I am also wondering about the notion of you buying them used at a Gamestop to begin with.
Either way, to answer the technical question, yes you can play copies of games if you burn them correctly.
That includes all the console games out there as well.