There was a release a couple weeks ago that let you sharpen the screen (or otherwise use a variety of filters) when playing DS(i) games. I think there were some updates or variations of it shortly afterward so I'm not exactly sure where it's posted.
That's only changing the upscale matrix used for scaling up DS games from 256x192 to 320x240 (or 384x240 if using the widescreen patch), but it doesn't actually influence how the display panel itself behaves or looks like.
I think that OP wants to make the display panel quality better in 3DS mode, which is possible, but the outcome is disappointing, and almost all settings in the LCD itself (not relevant to the LCD signal, but the display panel itself) are undocumented, unknown, and most of them have absolutely no visible effect when changed, so something the OP asks for is not possible yet.
The only thing possible is brightness increase (which has been done before), but the patches are abandoned to my knowledge because they crash gsp (Graphics Server/Service Process, basically the graphics and LCD driver (not really, but the details are irrelevant)). The other problem with the patching the brightness is that 3D mode requires different brightness curves, because the 3D grills block most of the light, so the backlight has to be compensated for the lost "appearent" brightness.