I can't seem to get this to work.. I have an older copy of Medicat I've been using and went to make a new version.
I first tried to make it with rufus + default settings, and when I boot it I get "Windows failed to start. A recent hardware or software change might be the cause." ... "0xc000000f" ... "A required device isn't connected or can't be accessed."
I then tried making the USB with the exact rufus settings listed in the main post, this produces a USB that isn't listed in my F12 boot menu.
In both instances I cannot launch it within Windows either; Autorun.exe -> Launch MediCat Menu -> "Could not find the PortableApps.com Platform main EXE: F:\PortableApps\PortableApps.com\PortableAppsPlatform.exe"
Same thing if I run F:\Start.exe and indeed the PortableApps folder is not present.
In case there was an issue with my drive I tried an alternate flash drive, to the same effect.
I also verified the MD5 of the ISO I downloaded.
I could understand it not booting because of an issue with UEFI, secure boot, etc.. but the not coming up with portable apps has me thinking there is a bigger problem.