I don't think I've actually played a DS game where I have cried although I do agree that the Elite Beat Agents level with the little girl is sad (where's the sequel that is so desperately needed?), and I was more shocked than sad with the original Phoenix Wright at the beginning of case 2.
On a less serious note, Animal Crossing.
On a less serious note, Animal Crossing.
Why won't you leave me alone Tom Nook? You buy my house, I pay my debt after crying at the amount I owe and then you convince me to upgrade to a better home. And it doesn't help that if I forget to save that a mole raises his voice at me.