I have one along with my 3DS XL.
The only minor gripes I have is I don't like the sleep switch. I guess you don't want it to accidenatlly be activated but it is not as easy to activate as i would like. Tiny child fingers have even more trouble with it.
I kind of miss the wireless switch as well. Not a fan of accessing it through software.
The other thing is the location of the Dpad. I feel pretty comfortable using it on my XL and play NSMB2 with the Dpad, but it is sort of awkward using it as the primary movement button on the 2DS. Maybe it just takes getting used to. Circle pad feels fine.
No clamshell does sacrifice some portability(it's still perfectly portable) but I believe it makes it more durable which is especially great for kids who have a tendency to crack the clamshells.
Overall if you don't want/need 3D it is perfectly fine.