Let's see... Infinite Space 3DS with updated graphics (with the pace of this game, they should be able to hike that graphics skirt waaaaaay up). Just imagining my fleet of battleships unleashing devastation in glorious 3D is making my ball sack squirm in delight. Fully voiced, too, by the looks of it. The audio levels has to be audible though. AUDIBLE, dammit.
Kaijuu Busters 3DS would also be awesome, and a strong contender in the Monster-Hunting genre (which so far, is led by Monster Hunter, followed by Gods Eater and other similar titles). Playing as Earth Defense Force soldiers, slaying giant monsters like Mothra and Eleking and Evil Ultraman. They even have two-men buggies in Kaijuu Busters Powered, much like the tank seen in MH4. Plus the always-awesome hoverboard weapon class, and the buffer-support backpack class (which is strong in its own right).
Cross Treasures 3DS (another JP exclusive). Awesome Action RPG with focus on looting and weapon forging. Strong end game challenge, and free class swapping is another great mechanic.