If you look in the "Other versions" section of that Wikipedia article, you'll see that a new version was recently published, written by Brian Clevinger of 8-Bit Theatre fame. Which is a more humorous/less serious version and has Spiderman in it. Haven't actually read it though, but I think his other works are pretty funny (8-Bit Theatre was fun, and I've actually bought his Atomic Robo comics), so I've been slightly interested in reading his version of The Infinity Gauntlet.
Hmmm.... but I don't think his version has Iron Man either, now that I think about it. So I have no idea what this game is based on.
Well, loaded it up, and it's in German. So, right off the bat, it's a no-go for me. However, just from the little bit of walking around I did, it's not like the last SHS game for DS. It seems more like Ultimate Alliance than the last UA for DS, which, for me, is a good thing. Look forward to checking out an English version.