If you're a first-time user, rectal suppository. It'll help prevent getting butthurt when you don't get it.
Once you're deep in the meme life, dank memes can be vaporized with a propylene glycol mixture or rolled in a Black & Mild for that refreshing, "I didn't have a dollar for a blunt, so I got this instead"-feeling.
You're in too deep when you're masturbating to memes.