In that case, do what it says, and either start TWiLight Menu++ from Unlaunch, or have Unlaunch auto-start TWiLight Menu++.for sega genesis only via picodriveTWL no Jnesis option. And for super nintendo it says " To launch this tittle, please restart TWiLight Menu++ from Unlaunch"
If you've already done so, make sure Limited Mode is turned off, as it's not recommended for everyday usage, and should only be used for testing in a DSiWarehax environment without an actual exploit.