OS ? You mean macOS Sierra ? I have it and Dolphin emulator runs Wii and Game Cube games great! PM me if you want for some emulators for macOS.. I will be happy to tell you the names of them. I have them on my macOS and don't have a problem. They works great!
You could also check out Lakka, a lightweight Linux distribution that basically offers you RetroArch as an OS, good if you're only using the computer for emulation and nothing else: http://www.lakka.tv
This is mostly for retro consoles. The OP didn't put much explanation into his/her post.