The Puzzle League part is the exact same gameplay as Tetris Attack/Pokemon Puzzle League/Pokemon Puzzle Challenge as far as I could tell, with more options you can choose in the options menu. However, there is NO story at all, a big letdown... The gameplay itself is great, I was just deceived was I saw the Jap release and hoped it would end up less bare-bones, but no...
There are still a good amount of game modes, along with 20 scales of computer AI difficulty, which should be a challenge for almost everyone, except the masters; I'm pretty sure they'd pwn the best AI...
Myself, I play usually around lvl 15 in Time Attack, the mode I play the most, and a "good game" for me is around 10k...
My best score, which I got on the Super NES in Multiplayer mode : 18 337
It might do a good introduction for pretty much everyone, since the AI fits for a wide array of players...
And for Dr. Mario, I didn't really check it that much, I'll others describe it here...
- Vince989