I blame the original Barbie NES game for making most girls of my generation hate videogames. (Growing up, I didn't know a single girl who liked them, but pretty much every single boy did.) Barbie was a horribly made platformer that was absolutely no fun.
I bet a lot of girls who expressed interest in video games were bought that by their parents or grandparents. Anyone who had that game as their first videogame experience would clearly never want to play another game again. Now that girls are finally starting to play games Barbie is back to turn girls away from them.