For me, Ghostbusters. I know the PC version will look better, and I'll still grab that one as well but the Wii version looks more fun and will be the first version I finish.
The Beatles: Rock Band is too expensive for a game and I also really lost interest in games that need fake instruments, people look like idiots when they play them. Another thing is I can already sing & play their songs.
The Conduit still looks too generic for me to care. I get a feeling that this will dissapoint many many people. Apart from being a FPS developed only for the Wii and having multiplayer I don't see what else it has to offer. I can't say I am THAT bowled over by the looks (not like that matters), the story sound like the typical sci-fi wank & the level design looks like it was done by amatuers.
Not seen enough of Dead Space: Extraction to want it.
Wii Sports Resort I need to know what is actually in it, Nintendo has shown nothing since last year. Also the games they did show (if they are still in) look boring.
Red Steel 2, thats a long way off! Ubisoft aren't even releasing it until next Spring (so they say) and also we've seen nothing that suggests that it'll be any good.
Punch-Out will surprise some people I feel, might be better than they expect it to be.
You've missed loads of games though! Overlord Dark Legend, Little King Story, Virtua Tennis 2009, Sin & Punishment 2 & Lets Tap (this will suprise many too) are just some that have been missed. I reckon Overlord may even better Ghostbusters for me...who knows.