Haha, I find it kinda funny how people are trying to adapt to this not being a run-of-the-mill ROM hack. So many questions being fielded on emulators to "wait, it's an exe"?? Not that we haven't seen this before, but still a funny little phenomenon. As to OP, no, afaik 3DS cannot run .exe files. They require Windows, and though they could be emulated, the 3DS's hardware could not handle it.