Might be a faulty rp2040. Did you remove the LDO from the back?SOOO. i have a V1 acting up. Sometimes the chip does not turn on (no light on the LED),and it opens OFW.
I have replaced gnd and 3.3v wires to 30 awg,same result.
I have "reflowed" the solder on the connections and still same result.
Here are some pictures
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