Nono, I meant sometimes because my Wii was hacked at 3.2 and I was able to load backups (this is when I could get to the title screen of MPT just unable to pick a game), then my friend came over, installed BootMii, and then he made my Wii up to date using the stuff in the stickied guide. Now I'm at 4.2 with DarkCORP and am unable to load the game through DarkCORP or even get to the title screen again using the loaders. I am pretty sure it is not a laser problem. I also have the Metroid Prime 1 Wii Controls version that was only released in Japan, and that used to get to the title screen and now it doesn't do that either (and the game is not dual layer).
As for what I'm using, it is burned onto an 8x Verbatim DVD+R DL, although for the reasons I said before, I am pretty sure that there is nothing wrong with the burn. However, my burn is of a NTSC Metroid Prime Trilogy, not PAL. Perhaps that has something to do with it?
Hope that clears everything up.