-The missing better half of Golden Sun Dark Dawn (it introduced new chars and all, but was more of a huge side-quest and opened tons of questions that were not remotely addressed, similar to GS1)
-A proper Final Fantasy Crystal Chronicles game (more like the original, less like the DS ones, but no way in hell any similar to bearers .-.)
-Super Metroid remake with Other M style gameplay
-new F-Zero that makes Mario Kart look lame
-proper Kirby game (no damn spin-off thing) ala Return to dreamland (really disappointed about available helpers and no animal friends), but with more non-story stuff (helper to hero was awesome in Ultra)
-a NEW pokemon game set in Hoenn 15 years after the events of Emerald (no damn remakes!). Tons of things changed, most gym leaders replaced by relatives/kids/friends/different gym, bigger focus on the rest of the legends, meeting the old hero and others, you get the idea.. but most importantly, a fix-upgrade to the first few generations of pokemon consisting of status readjustments (to get all those weak hybrids some use), some nobrainer type changes (Dragon for Gyarados, ditching Poison for Dark on Gengar, adding Psychic to Golduck etc), even some complete redesigns of particular pokes, an update to the type chart for balance reasons (giving Ice some resistances, make some stuff weak to poison etc)...yeah.
thats all I could come up with right now.