In my opinion, the guide at
http://www.wiiubru.com/guide/ is the best, since it lets you decide which hacking method you should use and tells you the advantages/disadvantages of each so you can make a decision. The wiiu.hacks.guide is probably similar though.
Although the guide I linked is "only for 5.5.1," all of the methods described in it work for 5.5.2/5.5.3 except for the web exploit; you can use the steps outlined at
https://gbatemp.net/threads/more-stable-webhack-for-5-5-2-5-5-3-released.528757/ to use the web exploit for those firmwares.
One final suggestion: use
https://jorgev259.github.io/wiiusetup/ to download your sd files properly and efficiently. And good luck!
Edit: oh, and to answer the question, the answer is yes. Any CFW you use should be region-free already, but if it still doesn't work, you can use a homebrew such as Spiik.