Yeah I've been using that one (Inf HP for primary character, Inf HP for Billy and Inf HP for Rebecca), and the only other one I've used is the 99 in Slot 1 for Rebecca.were you by any chance using the infinite health cheat?
that one sometimes didn't work for me until a reboot, if yes then that might be the problem
Though I do use the Inf Health ones more often, 99 Slot 1 I rarely use.