pstv @ 1080i for 4 hours "the Lost Child", with all trophies unlocked, no random crashes, but the enemies for about 3 fights did not load they were missing on screen before game crash. (after the 4 hour mark, I when to to the "loading screen" about 10 times before seeing missing enemies before game crash).
just for a note will try on 480p for 4 hours "the lost child", probably tomorrow and consider "PSVShell" best option, on max settings. (Danganropa V3, is the other one, and Borderlands) (expect the same result, but that solves it, the handheld vita plays at a lower resolution on any settings this may be pstv specific, already using minimal plugins) Goodluck.
(maybe this is true for the raspberry pi 4, when the official release is out, have to remember to do a test like this with dreamcast, a known memory mucher)
EDIT
"version 1.02 the lost child "fixed skills acquisition bug"
If you use the item that cost 10,000 for to help gain skills, and just nest in a battle without using attack skills, after a dozen or so skills the game will crash in under 2 hours, with normal play. i think this adds to the trophy bug thing.
noteworthy because its not the overclocking program causing the crash or memory leaks, the game does those on retail with no mods/hacks too - just deleted the game from my vita, but it was fun crashing it