that is wrong, its enabled by default. also "some games don't like this setting" is also completely wrong, its a very needed setting and should not be disabled at all.
as said its enabled by default, to actually disable it you would have to set "Unlock Read Speed" to On which I would not recommend because it would basically make load times be different each time you run a game, the default behaviour has a very set timing for everything so you can expect very similar loading results by default.
I cant tell you a whole list, its patched
in this file which gets applied to every single game, its 1.5x faster simply because the wii processor is 1.5x faster than the gamecube one and some games dont base their times on a global time or frames but on processor ticks passed, so that file basically patches all the known tick measurements to be equal to the wii ones so the games run properly.