Here is my list of compatibility for r250 (settings: wii, usb, shrinked isos, ocarina off, hid - ps2 controller, vmc on [59 blocks], progressive off, widescreen off):
1080 Avalanche - stucks on title screen pretty often. Before r249 run without any problems,
Baten Kaitos - works without any problems (music plays fine!),
Baten Kaitos Origins - works without any problems (music plays fine!),
Battalion Wars - works without any problems,
Beach Spikers - works without any problems,
Bomberman Generation - stucks on loading screen. Before r249 run without any problems,
Bomberman Jetters - works without any problems,
Donkey Kong Jungle Beat - works without any problems,
Eternal Darkness - stucks on poem screen (Edgar Allan Poe: "Deep into..."). Before r249 run without any problems,
F-Zero AX - works without any problems (save card isn't emulated yet),
F-Zero GX - works without any problems,
Kirby Air Ride - works without any problems,
Legends of Wrestling - stucks on loading screen (after movie intro). Before r249 the game also doesn't work,
Luigi's Mansion - the game works without any problems, but you can't watch "Pikmin Movie" (included in the options),
Mario Golf - works without any problems,
Mario Kart Arcade GP - works without any problems (save card isn't emulated yet),
Mario Kart Arcade GP 2 - works without any problems (save card isn't emulated yet),
Mario Kart Double Dash!! - works without any problems,
Mario Super Tennis - works without any problems,
Metal Gear Solid: Twin Snakes - works with one minor exception: controller doesn't work/respond on first screen (when you can choose to play with progressive on/off). I noticed that this is earlier problem than r249),
Soul Calibur 2 - works without any problems,
Spyro: A Hero's Tail - works without any problems,
Spyro: Enter the Dragonfly - works without any problems,
StarFox Adventures - stucks during first Fox McCloud mission (when you ends fly through rings - it's about 4% of game),
StarFox Assault - works without any problems,
Star Wars: Rogue Squadron II - works without any problems,
Star Wars: Rogue Squadron III - works without any problems,
Super Mario Strikers - works without any problems,
Super Mario Sunshine - works without any problems,
Super Smash Bros. Melee - works without any problems,
Virtua Striker 4 ver. 2006 - console turn off after boot,
Wario World - works without any problems,
Wave Race: Blue Storm - stuck on title screen. Before r249 run without any problems,
Worms Blast - works without any problems,
XGRA Extreme G Racing Association - stucks during loading the race pretty often. Before r249 run without any problems,
XIII - stucks during loading screen. Before r249 run without any problems (only with some lags in main menu).