It's likely fairly possible. What it comes down to is whether or not they have the exact same format and if the save has a secure-ish checksum. If they're 1:1, you can just savedatafiler it over. If they're not but there's no/a weak checksum, you can probably paste your important data (progression, items, etc) over from your old save with some careful hex editing and be fine.
I can't personally decrypt MH4G saves at the moment, so I can't specifically say which of these is true.