Longbaugh said:heres how i got it working with usbloader gx, dol from disc no workee for me
http://www.scribd.com/doc/19170103/Metroid-Prime-Trilogy-Alt
If alternative .dol loading from disc does not work but from sd, the question is which cIOS do you use? If it's not 13a, the game could be a 002b game, did you try anti 002 fix with alternative .dol loading from disc?
PS: And cIOSrev14 really can't play the game, so if you have cIOSrev14, that's why loading the .dol from disc does not work.