Yes, and I can confirm that it does work very nicely. So if your too classy to saw off the nub, you can just take apart a crappy DS game you don't play with a small flathead screwdriver. Here's a pic with the carts swapped. Notice the Ocarina of Time cart that isn't inside the 3DS, but is swapped with another DS game that is inside the 3DS.
So when a hack comes out, just swap carts and modify the save! Although once you take it apart, it makes pulling the top and bottom halves of the cart much easier, so hot glue is advised after doing this, unless you want your cart flying apart when you drop it.