You have to do it manually.How can i disable deflicker on cfg usb loader like usb loader gx?
Extract the dol file, open it with a hex editor and search for the exact strings to modify.
https://gbatemp.net/threads/possibl...-de-flicker-filter.477163/page-6#post-9473338
Then rename the dol with the first four letters of the game ID and finally activate alternative dol option in the loader settings.