Firstly, 12.0.0 es patches arent working yet so while the issue may be unrelated to sigpatches, you will still not be able to run them until you downgrade or patches are out (assuming they are nsp copies and not xci)
Secondly, theres two likely fixes to the issue. One is that it may be a sysmodule interference. Its not uncommon for certain games to conflict with sysmodules and not launch until the sysmodule is removed, so id try removing all sysmodules temporarily, easiest way is to rename the atmosphere folder and put on a fresh one from the atmosphere github with sigpatches and *nothing* else. Second possible fix is sometimes games cache bad data, and you can fix it by booting maintenance mode while launching the nand that the games are on. An example of how to do this would be to boot into rcm, hold volume up and down, while still holding them push fusee primary, then once you see the new unique menu let go of volume. Dont select any options in maintenance mode, just booting it clears the cache.