Yes i would beleive this is possible as this r4 card is a shameless gateway-3ds clone but the only problem is on the site it specifically says "Support 3DS V6.2.0-12" which this firmware is very old and probably unlikely of having it.
but on the flipside if you have 3ds 10.3 or under and you really wanted this card you could downgrade to 9.2 using sysupdater.
https://gbatemp.net/threads/tutorial-downgrade-3ds-with-sysupdater.407924/
then you could use gateway's launcher to downgrade to 4.5.
http://www.maxconsole.com/maxcon_fo...Downgrading-your-3DS-from-4-5-9-2-down-to-4-x
Although this would work you would be using firmware 4.5 on your sysnand and this r4 card creates an emunand for you to play the roms on, this website does not mention what firmware the emunand supports which makes me think you would be stuck with a firmware like 6.0.
honestly looking at if it supported gateways emunand since it is a clone you could probably use gateways emunand which supports 10.4 currently with that r4 card
-Happy Hacking