You're going to need the following to get it running:
no$gba 2.3b
eNDryptS Advanced v1.2
BIOSNDS7.ROM
BIOSNDS9.ROM
Put the BIOS files in the same directory as NO$GBA.EXE.
Put your ROM in the same directory as eNDryptS.
Run eNDryptS and make sure it successfully encrypts your ROM.
Put the ROM in your no$gba directory, run NO$GBA.EXE and load your ROM.
If the emulator can handle the game you're trying to play, there ya' go. There's a good chance it won't run as compatibility (in general) is low/medium on all DS emulators at the moment.