I have Aspergers. I don`t find it offensive.
People who aren`t stupid can laugh at themselves.
Whatever happened to the world? We just used to say Fuck off and that was the end of it without getting all Clinton-Snowflaked...
True, and also false. People who have it can laugh about it. But those who don't have a grasp over what they have, won't find it nearly as funny and more insulting. It really depends where you grown up. If you grown up in a childhood picked on you constantly for it, and your parents didn't help. You will find it even more annoying that if let's say someone who had some help on working with it.
To elaborate.
For me, I had learn some techniques that allowed me to work through my autism a bit better. It never goes completely away, any person who says that is bs. I still had a crappy school life until I moved.
But I know a friend who was less fortunate. Her parents don't really try to understand her, she had a terrible school. So when a joke is made about that she finds it beyond offensive. And she is by all means intelligent, she knows a shit ton about animals. Like, if you found a bug outside you didn't recognize, she would likely know exactly what it is, it's name, if it's toxic, it's unique characteristics to that species and so on. I didn't grow up in the same environment as she did, and she has extremely different reactions to what I have. She doesn't handle mental... issues... no where near as well as I do. Her first reaction would to be angry and bring up as many examples of why you shouldn't say that, my first reaction would to question and then react. But also take other peoples responses and consider those.
Some people handle jokes like that better
some people who are smart don't find those jokes funny
Not everyone functions the same.