This is my report :
Perfect :
Beneath a Steel Sky (0.0368 cd) => OK, smooth
Broken Sword : The Shadow of the Templars => OK, smooth
Broken Sword II : The Smoking Mirror => OK, smooth
Day of the Tentacle (CD/French) => OK, smooth
Discworld (CD/DOS/French) => OK, smooth
Flight of the Amazon Queen (Talkie/DOS/French) => OK, smooth
Full Throttle (French) => OK, smooth
Future Wars (DOS/French) => OK, smooth
Indiana Jones and the Fate of Atlantis (Floppy) => OK, smooth
Indiana Jones and the Fate of Atlantis (Steam) => OK, smooth
Lands of Lore : The Throne of Chaos (CD/DOS/French) => OK, smooth
Loom (FM-TOWNS) => OK, smooth
Lure of the Temptress (DOS/French) => OK, smooth
The secret of Monkey Island (CD/DOS/French) => OK, smooth
Monkey Island 2 => OK, smooth
The Curse of Monkey Island => OK, smooth
Simon the Sorcerer 1 (Floppy/DOS/French) => OK, smooth
Simon the Sorcerer 2 (Floppy/DOS/French) => OK, smooth
The Dig (French) => OK, smooth
The Legend of Kyrandia (CD/DOS/French) => OK, smooth
The Legend of Kyrandia 2 (CD/DOS/French) => OK, smooth
Zac McKracken and the Alien => OK, smooth
Playable :
Freddy Pharkas : Frontier Pharmacist (Floppy/DOS/French) => OK, not full speed (may be 90%), some crackling sound
King's Quest V : Absence Make the Heart Go Yonder (DOS/French) => OK, not full speed (may be 90%), some crackling sound
King's Quest VI : Heir Today, Gone Tomorrow (DOS/French) => OK, not full speed (may be 90%), some crackling sound
Laura Bow 2 : The Dagger of Amon Ra (DOS/French) => OK, not full speed (may be 90%), some crackling sound
Leisure Suit Larry 3 (DOS/French) => OK, not full speed (may be 90%), some crackling sound
Leisure Suit Larry 5 (DOS/French) => OK, not full speed (may be 90%), some crackling sound
Leisure Suit Larry 6 (DOS/French) => OK, not full speed (may be 90%), some crackling sound
Sam & Max Hit the Road (CD/French) => OK, not full speed (may be 90%), some crackling sound
Quest of Glory III : Wages of War (DOS/French) => OK, not full speed (may be 90%), some crackling sound
Space Quest I (SCI/DOS/English) => OK, not full speed (may be 90%), some crackling sound
Space Quest IV (DOS/French) => OK, not full speed (may be 90%), some crackling sound
Space Quest V (DOS/French) => OK, not full speed (may be 90%), some crackling sound
Not working :
Drascula: The Vampire Strikes Back (DOS/French) => (take a while to added, black screen at launch)
DreamWeb (CD/DOS/French) => "An error has occurred. The PS Vita system will be power off"
Indiana Jones and the Fate of Atlantis (FM-TONWS) => Erreur lors de l'execution du jeu : Unsupported color mode ( 16bit color support is required for this game)
Indiana Jones and the Last Crusade (VGA/DOS) => application crash (my version has OGG files for musics)
The Legend of Kyrandia 3 (CD/DOS/French) => black screen
Seems all Sierra games are not full speed because of chopped sound. I don't know if there is an option to choose in the settings (seems to don't change anything)