Al the packs I released recently are for Duckstation, I'm not doing Beetle anymore.
Duckstation has a few settings and it's annoying since not everything works on every game.
General settings that stay the same:
Enable Texture Cache
Enable Dumping
Enable VRAM Write Dumping
Always Track Uploads
Advanced:
Dump texture pages (Enabled most of the time, depends on game)
Reduce Palette Range ( I usually keep this disabled, except for MGS)
Texture Dumping Options:
Dump Size threshold: 1px by 1px, disable Alpha Channel
Background Dumping Options:
Dump Size threshold: 64px by 64px, enable Alpha Channel
When upscaling, keep the files PNG. Duckstation does not support DDS, jpeg and webp just doesn't seem to work.
Hope this helps