What I tried and worked fine: nes, snes, master system and megadrive. The o3ds isn't fast enough for GBA, so you better use Injects for that, also Gameboy classic and color didn't played well for me too, so for me the only way to play this console is via VC.
As Hayato213 said, no Vita.
Nes, Snes, Gameboy color, Gameboy advance, Nintendo DS (not emulation)
Sega Master System, Genesis/Mega Drive, Sega CD, 32x, Gamegear
Lots of arcade systems
Scummvm =retro pc point n click games