any card that's been updated since they stopped making ds games will not need AP patches on anything.
ysmenu, wood 1.62, etc...
An AP patch will not kill your save, unless the "i'm a pirate" flag is saved into the save file, in which case you generally have to start over.
This was an infamous problem with a certain RPG on ps2. once it tripped the anti piracy/cheat protection, and started crashing, you had to start all over and wipe the save or it would crash forever. if the antipiracy patch doesn't seem to fix anything, that's your problem.