I don't blame your cautious approach to tweaking your system settings... Linux is so finicky at times, I swear that looking at your distro of choice desktop funny or muttering anything bad about it only expedites something going wrong. Curses!Maybe i dont have the right dependencies only i install winehq and dont tweaked not to much the config. I dont tweak wine too much,because the last time i tweak it...occur some disasters in my old installation on Manjaro.
If you later decide to revisit getting NSUI to run on Manjaro, see the tutorial by @KleinesSinchen in that link in post #16.