Well, now that I'm thinking about it, the list that
@WulfyStylez posted means that I can safely update and still be able to have an exploitable system. I may lose cookhax, but I still have options. I'll have to get myself some DSi points and have them on reserve for when such exploit is released. I shouldn't have to worry about backing up my NAND, although I may lose my Acekard's ability to run.
Also, is TAD installation going to be possible with this hack? I know that there isn't a lot of these files in the wild right now, so piracy via TAD installation will be next to impossible because the format isn't known that well yet.