Yes and no, you will need to know the binary logic to program a Dualshock 4 and Xbox One Controller, and that's is not easy, the Wii U need to be hacked with homebrew channel U ( if it calls this...) and you need to make the app for the controllers, not to mention that you should be able to modify the games to make it compatible, but It can work with some apps like Nintendon't.
in short: you can use but only for applications like Nintendon't and emulators,but, for games but I very much doubt.
It's the same with the Wii, you can't use a Dualshock 3 or a Xbox 360 controller, and the Wii have the homebrew channel alredy...