Worth getting as someone who has never played a Fallout game before?
Same question. The TV show is the only toe I've dipped in this pool.
It's a uhhhh... hard question. First of all you gotta take in mind that one of the core aspects of Fallout games is their writing. They are for the most part satirical games that can also get very political at times
Fallout 4 is definitely the most different Fallout of all the main series. This is specially important regarding the RPG system
Every game before Fallout 4 follows a points system for skill (from 1-100) and a perk system every certain amount of levels that can give you special skills or advantages (more damage to X type of enemy, better critical chance on X factor, etc etc).
This has been tradition since the first Fallout. Fallout 4 really just has a general skill leveling system
On the other side of the coin, New Vegas and Fallout 3 are becoming old at this point (around 15 years old already) and require a lot of modding to work. They are really starting to show their age. There is also the matter that they are.. basically the same game? Fallout 3 and New Vegas were developed at the same time, sharing the same core from engine to gameplay to assets, to the point you can mod them to work together like a singular game.
Having said so, I personally (Like many) hold New Vegas in a special place on my heart as it's the most direct sequel to Fallout 2, (story-wise at the very least), made by Obsidian instead of Bethesda.
If you want to play a fun shooter with a coat of paint of "Fallout", then Fallout 4 is fine enough
If you want to know Fallout as it was intended to be, I would take New Vegas every day of the week, even if it takes some time modding. Writing is solid and gameplay is very fun. You can also gamble lol