Well I've finally updated my R4 to the CycloDS, and the first thing I want to say is this flash cart is physically SOLID. I never realized how flimsy the R4 was until I held the Cyclo at the same time. Overall, the CDSE seems pretty awesome. It can do most everything the R4 can and then some. My minor gripes: Something minor I missed that I never thought to research: The R4 automatically skips the Health Screen. The CycloDS doesn't. (Can live without) Something I knew, but dang: I was one of lucky to have a sping-loaded R4 that ALWAYS worked. I have a bad habit of chewing my fingernails, so removing the microSD card from the CDSE is rather complicated for me.