If your drive is Fat32 formatted, yes you can
If you don't have Fat partition then your options will be either make a FAT32 partition as first active and extract your wiiware games to Emunand (using your nand or ModMii or my premades) and setup WiiFlow to use that emunand (this option can let you install as much games as you like),
or just install the games on real nand and go to real nand mode (this would be fine if you're only planing to play a couple or 3 games.
Choose your pick