Dios Mios problem

I installed DM 2.10 a couple days ago, and configurable usb loader mod. I'm using DiscEx to convert iso into a compatible file. I started with Super Mario Sunshine, which ran perfectly, until I tried to go to Bianco Hills Secret or Rico Harbor. The game failed to load the other levels. I thought it was a problem with the iso file, so I've downloaded a new one, and while downloading it, decided to try Gauntlet Dark Legacy. Gauntlet ran fine, until I tried to enter level 2, and the game crashed. Now I'm thinking it's not so much a problem with the iso since two different games have experienced the same problem. Anyone have any ideas of what might be causing this and possible fixes?

 

no, Wii games from disc or from USB loader work fine.