I had the drive in WBFS format before, and because of the lag I formatted to fat32. I tried also different partition sizes 16GB and 130GB and with different cluster sizes 4-32kb, but no difference.
First I though the cluster size fixed the issue when playing around, but I had just reverted back to rev19, and didn't know that rev19 installer makes backup in 250. Is it so? So I though I still had rev20 in 250 what I used for testing, but actually I was testing with rev19 backup and thats why it was working. I have rev20 on 248 and tested that, and oh no lag is still there.
So my setup currently is
lags:
248 rev20 base 56
250 rev21 base 56
no lag:
249 rev19 base 57
hermes v4: 222 base 38, 223 base 37-38
Hermes v5.1: 224 base 57
Earlier I have had also 250 base 57 rev20 and it lagged