5. 999: 9 Hours, 9 Doors, 9 Persons (Zero Escape as it was renamed)
4. Infinite Space
1. Shin Megami Tensei: Devil Survivor 2
1. Shin Megami Tensei: Devil Survivor
1. The World Ends With You!
It's three on first place, I know, but, I just can't choose which of these is the best, so, all of them are the best.
Also, honorable mentions: Adventure Time, the Ace Attorney series, Pokemon series, Nodame Cantabile, Disgaea, Yu-Gi-Oh! series (as long as you like them, and I sure do), Professor Layton series, Spectrobes series, Tetris DS.