Uhh, Second blood?
I've ran both NEW blood and Second OPINION on a USB loader, and i have the same set up as you apart from the drive as i have a 250gb hard drive attached with a USB to IDE cable.
SO wouldn't load with GC stuff in and New blood hates being forced to anything.
Yeah, that program wouldn't work for ISOs.
Also no on the ruining the laser part.
It would only slow down loading times and put the motor that spins the disc under more stress, and they don't break often.
Uhh don't most of them do it the SD card way?
Just find channels that load the channels the SD way, or failing that, download them from the homebrew browser.
1. Which version of the USB loader, Most of the issues i had vanished after i upgraded, (and reformated unfortunatly).
2. Is this a partition of a drive or a whole drive, how big etc.
3. Can you still load games from it?
Yeah it works great but it's the obvious Ds factor you loose from it it's not like playing atari games on atari because Nintendo actually use to give a reason to buy their hardware
I just like game consoles how they were intended to play if they have a unique enough reason to buy them anything else yeah just download emulation for it