yes, and no
You can get channels for each of your wbfs game located on sd or usb.
You can't launch the channels without a loader (wiiflow/CFG for SD, Wiiflow/CFG/USBLoaderGX for USB).
the channel is in fact a forwarder, which launches one of your USB Loader but sends a game's titleID as argument with "autoboot" information.
The loader is then responsible for selecting the wbfs file and launching it using the setting you set for that game (language, video mode, cheats, etc.), except that it launches right at loader's start. with some loaders, you don't even see that a loader is being launched.
you can see it like this : the loader is the place where you set the game setting, the channel is the place where you launch the game.
channel -> launch a game loader -> game loader autoboot the game
here is the program you use on your computer to generate the channel that you will install on your system menu using a wad manager :
http://www.wiidewii.com/read.php?28,26965,34837
I don't know if it's the latest version.
Attention, it was known that some games could brick your system menu (banner brick), be sure you have Priiloader or Bootmii@boot2 before installing wads.
(a boy and his blob, or Mario party 9 are banner bricking. I think aboy&blob has a protection in Wiigsc and will refuse to make it a channel, I don't know about other games)