Had this problem a while ago also, seems to be connected to the video settings conflicting somehow. I will not get into that argument anymore...A very strange and disconcerting error occured - I was using the Neo-Geo core, and upon loading bangbead.zip it had loaded an incorrect palette (sort of brownish-purplish) and ran at half speed, the weird thing is this carried over even after I left retroarch, the homebrew channel ran with incorrect colors and at half speed! there is no problem with the game itself as I had loaded it fine afterwards, but just something really weird and similar to what happened to another user before (although I had not left the console running for several hours beforehand and didn't have to do with resolution settings). Unfortunately I don't know how to reproduce it, sorry...
On another note, I am completely blown away by the fact that space bomber and gunbarich run fullspeed!
Offtopic: Does anybody have a master list of working FBA games in conjunction with Retroarch Wii , sorted to system?( CPS1&2, NeoGeo, Other boards)
I'm trying to get my collection up to date and this would probably speed things up.