No way to use 4TB NTFS drive to play backups. You can either use 2TB FAT32 to play or use 4TB NTFS to copy into internal hard drive.
Another issue is >4GB file split. For FF13, you have to split some larger video files in the FAT32 external drive.
btw i feel this a good time to remind you guys that sea of thieves was made by rare, who also made DKC1-3 and DK64, alongside banjo kazooie and conker's bad fur day