if is your acekard 2i fixed for 1.4 fw (Danny Phantom icon on the menu) than you can update to 1.4 without any problems.... i think that dsi is region free, there is no difference between e,u,a...only the dsiware content is a bit different
definitelly golden sun ds,dragon quest IX, dragon ball origins 2 and okamiden( okamiden is announced at Q1 2011 so it come out this year) if it must be ONE it is GOLDEN SUN DS
if you have ak2i than you must hold X while loading the game till the loading word turns to a red one...of course you must have venoms version of game....
I didn't know they made an MSU cart for the Genesis.... I knew about the SNES one and the library for that is rather large but the Genesis one has very few games